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  • Defects In The Factor V Gene
    701 words
    The genetic disorder which I have chosen as the subject of my report is hemophilia. There are two types of hemophilia, hemophilia-A and hemophilia-B. The clinical symptoms of both are very similar so for the purposes of this paper I have chosen to concentrate on hemophilia-A. Hemophilia-A is an X linked bleeding disorder resulting from a defect in a protein known as coagulation factor V. Since the disorder is X linked it is expressed mainly in males, who must have mothers who are carriers. Femal...
  • Hemophilia B Lack Factor IX
    2,870 words
    Hemophilia is the oldest known hereditary bleeding disorder. There are two types of hemophilia, A and B (Christmas Disease). Low levels or complete absence of a blood protein essential for clotting causes both. Patients with hemophilia A lack the blood clotting protein, factor V, and those with hemophilia B lack factor IX. A person with severe hemophilia has less than 1% of the normal amount of a clotting factor - either Factor V (8) or Factor IX (9). People without hemophilia have between 50-15...
  • More Factor V Replacement Therapy
    1,036 words
    ... As more blood leaks into the joint it feels warmer than the opposite one and the swelling feels 'spongy'. Later the person holds the limb in a bent or 'flexed' position to ease pain. Flexion increases the space in the joint, making more room for further bleeding to occur. If untreated, the bleeding continues until the area feels hot and rock hard. Usually there is no bruising associated with a joint bleed, and since the bleeding occurs in an enclosed space (the joint capsule) and has nowhere...
  • Clotting Factor V
    1,033 words
    In the human body, each cell contains 23 pairs of chromosomes, one of each pair inherited through the egg from the mother and the other from the sperm of the father. Of these chromosomes, those that determine sex are X and Y. Females have XX and males have XY. In addition to information concerning sex, the X chromosomes carry determinants for a number of other features of the body, including the levels of factor V and lX. If the genetic information determining factors V and lX is defective, hemo...
  • Factor V And IX Blood Levels
    1,209 words
    (1) In the human body, each cell contains 23 pairs of chromosomes, one of each pair inherited through the egg from the mother, and the other inherited through the sperm of the father. Of these chromosomes, those that determine sex are X and Y. Females have XX and males have XY. In addition to the information on sex, 'the X chromosomes carry determinants for a number of other features of the body including the levels of factor V and factor IX. ' 1 If the genetic information determining the factor...

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